Can Not Having Enough Vitamin D Make My Rheumatoid Arthritis Worse,Nike Free 3.0 v2 Women røde sorte sko
In addition to the other health problems associated with vitamin D deficiency, there is another one. Not having enough vitamin D can make rheumatoid arthritis (and other inflammatory arthritis,Nike Air Max 90 sorte sko, possibly) symptoms worse. These findings were reported recently by researchers in the United Kingdom.
In the July issue of Arthritis and Rheumatism,Rabatt MBT Schuhe, Dr. Sanjeev Patel of St. Helier University Hospital, Carsholton, and colleagues note that there is evidence that vitamin D and its metabolite 25-hydroxyvitamin D (25[OH]D),Dame Air Force 1 Low Easter Egg Edition Red, in particular,Nike Air Max 90 Neutral Grey Mean Green, may have immunomodulatory effects. (Patel A, Farragher T, Berry J, Bunn D,Nike Free 7.0 V2 Blå Mørke Grå Sko, Silman A,Nike Air Max 2011 Herre Gray blå sko, Symmons D. Association between serum vitamin D metabolite levels and disease activity in patients with early inflammatory polyarthritis.of Arthritis Rheum 2007;56:2143-2149).
Metabolites are what vitamin D is converted to in the body. Conversion to different forms of the vitamin can occur in the liver or kidney. Conversion is a common process. Many drugs taken for different diseases undergo this process. In fact, often the metabolite is the active form of the medicine or vitamin. In the case of vitamin D,Rabatt Frauen MBT Sandalen Sadiki purpurnen, there are two active metabolites: 25-hydroxyvitamin D and 1,Dame Nike Free Run 2 Grå Gul Hvid Sko,25-dihydroxyvitamin D.
The investigators wanted to find out whether metabolites of vitamin D might have an influence on polyarthritis.
Polyarthritis means a type of arthritis that affects many joints. The prototypical form of polyarthritis is rheumatoid arthritis.
The researchers measured serum levels of 25(OH)D and 1,25- dihydroxyvitamin D (1,25[OH]2D) in 206 patients within 6 months of the onset of symptoms of their disease.
They observed an inverse relationship between baseline levels 25(OH)D and multiple measures of disease activity. In other words, the lower the vitamin D metabolite levels were, the more symptoms a patient had.
In particular,Nike Air Force 1 All Star Sort Rød, one measure- the Health Assessment Questionnaire or HAQ- is a common measure of how a patient feels. The researchers found that at baseline, 1,25(OH)2D levels had an inverse relationship with HAQ scores. At 1 year, baseline levels of both metabolites continued to have a significant inverse association with HAQ scores.
According to Dr. Patel, "The results of this study show that vitamin D deficiency may increase rheumatoid arthritis activity. We need to study this further and see if giving vitamin D or more potent drugs with vitamin D activity can relieve symptoms of rheumatoid arthritis."
So what is the message for you if you have rheumatoid arthritis? Make sure your rheumatologist checks your vitamin D levels routinely, particularly in the winter when vitamin D levels can plummet.
If your vitamin D levels are low, you need replacement therapy. In our practice we have noted that patients with vitamin D deficiency often have more flares than patients who have normal vitamin D levels. Vitamin D levels in our patients are monitored routinely. 相关的主题文章：
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